Eosinophilic leukaemia with trisomy 8 and double gammopathy.

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Eosinophilic leukaemia with trisomy 8 and double gammopathy.

Prolonged eosinophilia of unknown cause has generally been described as the hypereosinophilic syndrome, and is characterised by peripheral blood and bone marrow infiltration and frequent multisystem disease. The nature of this disorder has been questioned, and the clinical features are quite variable, suggesting its heterogeneity and probable neoplastic aetiology. A patient with severe eosinoph...

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Eosinophilic leukaemia in association with a double Philadelphia chromosome.

A case of eosinophilic leukaemia in association with chromosomal abnormalities including a double Philadelphia chromosome is reported. Comment is also made on the cardiological problems which arise in this condition.

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Eosinophilic leukaemia terminating with an encephalopathy.

A 52-year-old man developed an illness which lasted for 2 years until its fatal termination. It comprised in chronological order: mild asthma, skin irritation, mature eosinophilia in the peripheral blood, and finally an encephalopathy. The diagnostic problem of distinguishing between eosinophilic leukaemia and an eosinophilic leukaemoid reaction is discussed. The cause of the encephalopathy was...

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Eosinophilic leukaemia in a cat.

A 14-year-old female domestic shorthair cat was presented to Tehran University Veterinary Teaching Hospital for a persistent fever, anorexia, intermittent vomiting, weight loss and weakness. The main clinical signs were pale mucous membranes, dehydration and splenomegaly. The complete blood count and serum biochemistry tests revealed non-regenerative anaemia, thrombocytopenia and increased alka...

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Double autosomal trisomy (trisomy D+G) with mosaicism.

The patient, a male, the seventh child of a 37-year-old father and a 34-year-old Caucasian mother, was the product of a pregnancy complicated by massive polyhydramnios. The mother previously had had two miscarriages. During the present pregnancy she had not had any infections or X-irradiation. There was no family history of congenital malformations, mental retardation, leukaemia, autoimmune dis...

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ژورنال

عنوان ژورنال: Journal of Clinical Pathology

سال: 1993

ISSN: 0021-9746

DOI: 10.1136/jcp.46.7.672